Chiellini Icardi is the second best striker Ive ever faced

first_imgJuventus captain Giorgio Chiellini has faced off against numerous amounts of world-class strikers across his playing career and rates Mauro Icardi as one of the bestThe Inter Milan star is one of the most highly-regarded forwards in European football right now and has been frequently linked with a move to Real Madrid.In total, Icardi has scored 119 goals in 200 appearances for Inter and has found the net against Juventus eight times since arriving at Italy in 2011.And Chiellini has nothing but respect for Icardi, who he rates as the most deadliest striker in the penalty area behind team-mate Cristiano Ronaldo.“In my opinion, Icardi is the second best striker in the penalty box who I’ve ever marked,” Chiellini told DAZN, via Football-Italia.“He chips away at you mentally, in the sense that you have to be concentrated all the time. I’ve only encountered one who is worse for that, but he’s playing with me this year!”The Italian defender then gave his take on the downside of Juventus’ campaign this season.Serie A, Gian Piero GasperiniGasperini reveals why he rejected Inter Manuel R. Medina – September 14, 2019 Atalanta manager, Gian Piero Gasperini, has revealed why he rejected Internazionale Milan’s job proposal over the summer transfer window.Massimiliano Allegri’s side finished top of Group H in the Champions League on Wednesday night, despite losing 2-1 to BSC Young Boys in their final game, and already lead the Serie A by eight points from nearest challengers Napoli.But Chiellini highlighted October’s 1-1 home draw with Genoa and their 2-1 defeat to Manchester United last month as low points in their season.“There are some, like that draw we had with Genoa. Those were definitely two points dropped, and with all due respect for Genoa we can’t afford to drop points to them at home,” said Chiellini.“We’ve also been at 1-0 close to the end too many times. It’s almost always been fine because of our attitude, but against Manchester United we paid for it with interest.“I’d say 1-0 is a perfect result up until about 60 minutes, then you need to get the second and manage things better.“Not conceding gives you confidence for the next games, but having a little cushion means you expend less physical and mental energy.”last_img read more

JAST commended for contribution to sugar industry

first_img Related Items: Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsAppMontego Bay, Jamaica, November 8, 2016 – The Jamaica Association of Sugar Technologists (JAST) has been commended for its contribution to the sustainable development of the sugar industry over the last 79 years.Addressing the opening of the 79th Annual Conference of JAST at the Riu Hotel in Ocho Rios, St. Ann, on November 3, Mr. Samuda said the association continues to play a fundamental role in endorsing technology in the industry. “I want to congratulate the Jamaica Association of Sugar Technologists for having survived over these many years and for the tremendous and significant contributions you have made to the development and survival of the sugar-cane industry. Your role is, therefore, critical as we seek to reposition the sugar industry,” the Minister said.Mr. Samuda emphasized that now more than ever, the efforts of JAST must be doubled in order to save the industry. “We are grappling with the challenges that confront Jamaica’s sugar industry every day and now we have to position not only the existing players in the industry, but we have to introduce new ones. We must also seek to make the industry very attractive for new investments,” the Minister said.He pointed out that the sugar industry is the second largest employer of workers in the country, hence it cannot be allowed to die. “Because of this high level of integration and the fact that the industry is so integral to people’s lives and livelihood, we must remain committed to its success and so ensure its viability,” Mr. Samuda told the large group of participating members of the farming community.He informed that efforts at reforming the sugar industry were successful, as the Government assumed temporary operations of the Long Pond Factory in Trelawny and immediately initiated plans to attract new investment for the industry in that parish. The Minister invited investors, both local and foreign, to come forward and take part in the sugar industry.last_img read more

HOT OFF THE PRESS Read Wilmington Senior Centers October Newsletter

first_imgWILMINGTON, MA — Read the Wilmington Senior Center’s October 2018 Newsletter HERE.Highlights from the latest “Buzzell Buzz” include:Notes from Elderly Services Director Terri MarcielloInformation on the Community Teamwork’s Fuel Assistance ProgramInformation about upcoming events, including: Fire Safety & Prevention Month Event; Meditation Classes; Grand Opening of “Our Moment Cafe;” Visit to Wilmington Arts Council; the Buzz Book Club; the Caregivers Support Group; Wilmington Has Talent Holiday Edition; Fire & Fall Prevention Program; Homestead Seminar; Game Night; Pumpkin Decorating; and Doris’ Craft CornerInformation about: Birthdays, Condolences, Guess Who Contest?, and Get Well Wishes.The Senior Center’s October Calendar of EventsLike Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedHOT OFF THE PRESS: Read Wilmington Senior Center’s September NewsletterIn “Community”HOT OFF THE PRESS: Read Wilmington Senior Center’s August NewsletterIn “Community”HOT OFF THE PRESS: Read Wilmington Senior Center’s July NewsletterIn “Community”last_img read more

Trump Rouhani exchange threats insults at UN

first_imgUS president Donald Trump addresses the 73rd session of the United Nations General Assembly at UN headquarters in New York, US on 25 September. Photo: ReutersUS president Donald Trump and Iranian president Hassan Rouhani exchanged taunts at the United Nations General Assembly on Tuesday with Trump vowing more sanctions against Tehran and Rouhani suggesting his American counterpart suffers from a “weakness of intellect.”Trump used his annual address to the United Nations to attack Iran’s “corrupt dictatorship,” praise last year’s bogeyman North Korea and lay down a defiant message that he will reject globalism and protect American interests.But much of his 35-minute address was aimed squarely at Iran, which the United States accuses of harbouring nuclear ambitions and fomenting instability in the Middle East through its support for militant groups in Syria, Lebanon and Yemen.“Iran’s leaders sow chaos, death and destruction,” Trump told the gathering in the green-marbled hall. “They do not respect their neighbours or borders or the sovereign rights of nations.”Rouhani, addressing the assembled world leaders later, sharply criticized Trump’s decision to withdraw from the 2015 international nuclear deal with Iran. He said he had “no need for a photo opportunity” with Trump and suggested the US president’s pull back from global institutions was a character defect.“Confronting multilateralism is not a sign of strength. Rather it is a symptom of the weakness of intellect – it betrays an inability in understanding a complex and interconnected world,” he said.Trump’s address was met largely by silence from world leaders still not comfortable with go-it-alone views that have strained US relationships with traditional allies worldwide.His speech, while delivered in a low-key fashion, was nonetheless a thunderous recitation of his “America First” policies. He has disrupted the world order by withdrawing the United States from the nuclear deal and the Paris climate accord, and threatened to punish NATO nations for not paying more for their common defence.“We will never surrender America’s sovereignty to an unelected, unaccountable, global bureaucracy,” Trump said, in language popular with his political base. “America is governed by Americans. We reject the ideology of globalism, and we embrace the doctrine of patriotism.”Besides calling out Iran, Trump also criticized China for its trade practices but made no mention of Russia’s interference in Syria’s war or its suspected meddling in US elections.Rouhani was defiant in his speech to the world body.“What Iran says is clear: no war, no sanctions, no threats, no bullying; just acting according to the law and the fulfillment of obligations,” Rouhani said.Macron’s Alternative ViewOffering an alternative view when it was his turn at the podium, French president Emmanuel Macron told the delegates that the law of the survival of the fittest, protectionism and isolationism would only lead to heightened tensions.Defending multilateralism and collective action, he said nationalism would lead to failure and if countries stopped defending basic principles, global wars would return.“I do not accept the erosion of multilateralism and don’t accept our history unraveling,” Macron told the assembly, at times raising his voice. “Our children are watching.”Macron, citing the example of Iran, said that this unilateralism push would lead directly to conflicts.Trump, who begins his political rallies with boasts about his economic record in less than two years in office, used the same rhetoric before the crowd of world leaders and diplomats, telling them he had accomplished more than almost any previous US president.The remark led to some murmuring and laughter in the crowd, taking the president slightly aback.“I didn’t expect that reaction, but that’s OK,” he said.Trump attempted to drive a wedge between Iran’s leadership and its people, days after an attack in southwestern Iran on a military parade killed 25 people and unsettled the country.In remarks to reporters on his way to his speech, Trump said he would not meet the Iranians until they “change their tune.” Though he held out the possibility of a better relationship in the future, he made clear economic pressure on Iran would not abate.Trump’s national security adviser, John Bolton, addressing a group called United Against a Nuclear Iran, called the 2015 accord “the worst diplomatic debacle in American history” and had a warning for “the mullahs in Tehran.”“If you cross us, our allies, or our partners; if you harm our citizens; if you continue to lie, cheat, and deceive, yes, there will indeed be HELL to PAY,” he said.In May, Republican Trump withdrew the United States from the deal to put curbs on Iran’s nuclear program in exchange for easing sanctions. France, Britain, Germany, Russia, China and the European Union were part of the accord with Iran.Foes for decades, Washington and Tehran have been increasingly at odds since May. The accord with OPEC member Iran was negotiated under Democratic US president Barack Obama.“Additional sanctions will resume 5 November and more will follow and we are working with countries that import Iranian crude oil to cut their purchases substantially,” Trump said.He said the United States would help create a regional strategic alliance between Gulf nations and Jordan and Egypt, a move the United States sees as a bulwark against Iran.Trump compared US relations with Iran to what he called improved ties with North Korean leader Kim Jong Un, who Trump had met in Singapore in June as part of a still-unfulfilled drive to get Pyongyang to give up its nuclear weapons.In his address last year to the UN, Trump insulted Kim as a “rocket man” bent on nuclear destruction. On Tuesday, Trump praised Kim for halting nuclear and missile tests, releasing Americans held prisoner and returning some remains of US soldiers killed in the 1950s Korean War.The two leaders are trying to arrange a second summit. Trump has said sanctions on North Korea would remain for now.Delivering a harsh message to OPEC members, Trump called on them to stop raising oil prices and to pay for their own military protection. He threatened to limit US aid only to countries that are friendly to the United States.Anwar Gargash, UAE minister of state for Foreign Affairs said oil prices were driven only by markets, by supply and demand. “These are not things that can be manipulated by a decision here or there,” said Gargash, whose country is an OPEC member.Crude oil prices shot to a four-year high on Tuesday, catapulted by imminent US sanctions on Iranian crude exports and the apparent reluctance of OPEC and Russia to raise output to offset the potential hit to global supply.last_img read more

Uhoh Intel Globalfoundries to fastforward into 14nm

first_img Citation: Uh-oh, Intel. Globalfoundries to fast-forward into 14nm (2012, September 24) retrieved 18 August 2019 from https://phys.org/news/2012-09-uh-oh-intel-globalfoundries-fast-forward-14nm.html © 2012 Phys.org This is a nonplanar architecture optimized for low-power, mobile system-on-chip (SoC) designs. These chips will deliver a 40 percent to 60 percent improvement in battery life compared to two-dimension planar transistors at the 20nm node. Globalfoundries will go “3-D” in the use of three-dimensional “FinFET” transistors. The big deal about “FinFET” rests in its promoted superior low-power attributes. The FinFET architecture takes a traditional two-dimensional transistor design and turns the conductive channel on its side, resulting in a three-dimensional fin structure, surrounded by a gate controlling the flow of current. The 3-D transistor design operates at a lower voltage with minimal current leakage. This leads to a longer battery life for mobile applications and less power consumption for plugged-in applications. The power-consumption advantage could have important implications for networking chips in data centers.Intel’s challenge is not only in the rival company’s technology but also in 14nm timelines. Globalfoundries is speeding up its timeline for its 14nm process. Chip watchers note that in so doing it is playing leapfrog over other companies. The company will be ready to roll with a 14-nanometer process that will include its three-dimensional transistor architecture. This is said to be similar to Intel’s Tri-Gate method. Enthusiasts say that the 14nm-XM design is expected to carry performance and power benefits of three-dimensional FinFET transistors, possibly influencing a newer generation of mobile devices.With the Globalfoundries plan, chip designers will be able to start producing sample 14 nanometer chips in 2013. In 2014 or early 2015, the 14 nm chips will be part of the consumer marketplace. Technology development of the 14nm-XM has begun in Globalfoundries’ Fab 8, a fabrication plant in Saratoga County, New York. The company is making early process design kits (PDKs) which are available now. Customer tape-outs—the final result of the design—are expected in 2013. Globalfoundries was formerly a manufacturing arm of AMD. Headquartered in Milpitas, California, Globalfoundries now counts itself as one of the largest foundries in the world by revenue. Imec releases industry’s first 14nm process development kit More information: www.globalfoundries.com/technology/14XM.aspx Explore further (Phys.org)—Globalfoundries has made an announcement that amounts to a direct challenge to Intel, in the latter’s race to get further ahead in the mobile device ecosystem. Both Globalfoundries and Intel will be racing for a more dominant position with higher performing and power efficient systems for smartphones and other devices. In short, Globalfoundries announced Thursday that it is accelerating its technology roadmap. Its newest design achievement for the mobile market is in the form of 14nm chip technology. The company provided some details about its 14nm-XM (“extreme mobility”) process. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Learning physics may activate new brain areas

first_imgBrain areas that are traditionally not associated with learning science can become active when people are confronted with solving physics problems, finds a study. This shows that the brain’s activity can be modified by different forms of instruction.”The neurobiological processes that underpin learning are complex and not always directly connected to what we think it means to learn,” said lead author Eric Brewe, Associate Professor at Drexel University in Pennsylvania, US. Also Read – Add new books to your shelfThe findings, published in the journal Frontiers in ICT, showed that newer brain regions associated with attention, working memory and problem solving – the lateral prefrontal cortex and parietal cortex, sometimes called the brain’s ‘central executive network’ – showed activity when dealing with such problems.Another area that became active was the posterior cingulate cortex, which is linked to episodic memory and self-referential thought.”These changes in brain activity may be related to more complex behavioural changes in how students reason through physics questions post- relative to pre-instruction,” Brewe noted. Also Read – Over 2 hours screen time daily will make your kids impulsive”These might include shifts in strategy or an increased access to physics knowledge and problem-solving resources,” he said.Using fMRI (functional magnetic resonance imaging) to measure blood flow in the brain, the researchers looked to map what areas become active when completing a physics reasoning task, both before a course on the concepts and after. A small group of students were taught a physics course that utilised ‘Modeling Instruction’, a style of teaching which encourages students to be active participants in their learning. “This suggests that learning physics is an imaginative process, which is not typically how people think of it,” Brewe said, in reference to the study which aimed to explore how students use their own mental models to understand new concepts.”The idea of mental models is something that people who research learning love to talk about, but have no evidence of what is happening inside brains other than what people say or do,” Brewe said. “We are actually looking for evidence from inside the brain,” he added.last_img read more

It sounds like the ultimate white savior movieOsc

first_imgIt sounds like the ultimate white savior movie.Oscar-winning actress Brie Larson plays a young scientist who has created a new fast-growing super-rice. She comes to India to convince villagers to switch to this grain. There’s Bollywood-style singing, dancing — and in one scene she even rides a white horse!Called Basmati Blues, the Hollywood film was made in 2013, before Larson was a star. But it’s just now coming out. When the trailer was released in November, with scenes of Larson dressed in elaborate Indian costumes and recoiling from spicy food, Indians around the world took offense, calling out its stereotypes and cliches.The movie is finally being released in the U.S. on Friday, playing in select cinemas and available via video on demand. Critics have not been kind. The L.A. Times called it “a big miss,” while the Village Voice wondered how it “this thing got financed and finished.”In the film, Larson’s character, Dr. Linda Watt, is sent to the southern state of Kerala in India. Gurgon, her greedy corporate boss, played the actor Donald Sutherland, wants her to convince local farmers to switch to the new rice: “India: 500 million farmers, 1.1 billion rice eaters, all of them … potential customers,” Gurgon declares with glee.The problem is that the rice she’s recommending could financially destroy the very people she means to help. The rice is sterile. If farmers grew it, they’d need to spend a lot of money to buy new seeds every year.Along the way, she falls in love with a farmer, who actually trained as a scientist but had to drop out of university. Rajit, as he’s called, is played by American-born actor Utkarsh Ambudkar, who’s appeared in the movies Pitch Perfect and on TV shows like The Mindy Project.The controversy around the film started in November, after the international trailer was released. That’s where the white horse made its appearance, which Linda rides while trying to halt a train loaded with the super-rice.”It plays to stereotypes of an exotic but backward people just waiting for a white person to swoop in and save them,” says Bengaluru-based cartoonist, Manoj Vijayan, in an interview with NPR.That sentiment was shared by people across Twitter.Following the backlash, director Dan Baron and his wife, Monique Caulfield, who produced the film, issued an apology and withdrew the trailer. In a statement to the blog Refinery29 in November, they said: “We deeply regret any offense caused by the Basmati Blues trailer. We have heard a number of voices that have understandably reacted to a trailer that is not representative of the film as a whole.”In January, a new trailer was introduced to the Basmati Blues website, with the white horse scene deleted.The criticism on Twitter however, raged on.The film’s white savior message isn’t the only issue that rankles. “The script seems to have gone overboard with its lazy cliches, the lame jokes and the stereotyping,” says Vijayan. “It’s a sadly missed opportunity to tell a story with some nuance and ends up pandering to tired old preconceptions.”In the scene where Larson first meets Rajit, he greets her while hanging upside down from the roof of a train while she’s seated at the window, as though hanging like possums on trains was perfectly normal in India.In an interview with NPR, Jaya Padmanabhan, an immigration columnist for The San Francisco Examiner, shared some advice for the filmmakers: “Someone should tell Baron and Jeff Dorchen [who wrote the screenplay] to visit India without a camera obstructing their worldview.”Kamala Thiagarajan is a freelance journalist based in Madurai, South India. Her work has appeared in The International New York Times, BBC Travel and Forbes India. You can follow her @kamal_t Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

Amazons Whole Foods Deal Will Remake Strip Malls

first_imgAmazon Add to Queue What happens to small businesses if grocery stores shut down? Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals –shares The implications of Amazon’s $13.7-billion Whole Foods Market purchase will go significantly beyond the world of grocery stores, potentially reshaping retail districts in downtowns and suburban shopping areas across America.Not long ago, the typical American strip mall had a video store, music store and a supermarket. However, Napster and iTunes slayed the neighborhood music store, Blockbuster’s 9,000 video stores were killed by Netflix, and now the local grocery store will get a makeover. It’s a change that will reimagine how we shop and create commercial real estate investment opportunities.Amazon’s purchase of Whole Foods dramatically changes the $674-billion U.S. grocery market. On the day the deal was announced, competitors across the board — from Walmart and Costco to Kroger and Sprouts Farmers Market — lost a combined $22 billion of market value. That loss came because investors expect Amazon to utterly transform the grocery business.Related: The Winners and Losers in Amazon’s Whole Foods DealWhat’s so scary about Amazon? It makes every business it competes with efficient, squeezing waste out of the supply chain and compressing margins for the entire industry. Now, Whole Foods’ 450 stores in 42 states will form the start of a nationwide distribution center for groceries that will build upon the Amazon Fresh grocery delivery unit, founded in 2007.All Whole Foods’ stores won’t close, but they will change. Yes, customers will always want a neighborhood store for the touch, smell and feel of certain things — to pick up steaks for a dinner party, for fresh pastries and crisp lettuce. However, Amazon won’t stock high-priced downtown real estate with excessive amounts of paper towels and floor cleaning products, or even dry goods such as pasta or canned beans. The mass of these items will instead be stored and distributed from regional warehouse facilities, perhaps automatically shipped directly to customers using predictive models. As a result, the average size of a typical Whole Foods store most likely will shrink, as will the average grocery store across America.Some supermarkets will stay the same, for people who don’t like shopping online or prefer a trip to the store. Most competitors, however, will adapt to the Amazon model, shrinking their footprint and bolstering online capabilities to become more efficient and automated. Large grocers must now change their business model or go the way of the dinosaur.Related: 8 Interesting Tidbits From Whole Foods’ Town Hall Following the Amazon AcquisitionThis will create significant disruption in commercial real estate as countless supermarkets go out of business, others remodel to occupy a smaller footprint, and some move to new premises. We saw similar disruption after the 2008 financial crisis when thousands of car dealers across America went bankrupt as credit dried up and countless supermarkets closed as property prices crashed. A repeat of that dynamic in the grocery sector will be a significant opportunity for investors in distressed assets. At Northstar Commercial Partners, for example, after the crisis we bought five vacated Albertsons stores in Colorado for less than 10 percent of their replacement value. Each of these were repositioned into alternative uses at attractive prices.Investing in such properties, when they become available, requires a creative approach to what could work in the space, whether it’s a single business or remodeling the space to create a series of smaller units. In the case of those Albertsons stores, for example, one is now occupied by an antique dealer, another by a college that wanted a neighborhood presence.In the coming years, spaces now occupied by supermarkets will become children’s play centers, business incubators, leisure centers and even charter schools. Real estate developers and investors attuned to what will appeal to the local officials charged with revitalizing retail districts will find powerful investment opportunities. The properties vacated by the coming grocery transformation will be sold by real estate investment trusts that are overexposed to assets with declining cash flows, companies selling property to invest in operations, as well as by banks that will foreclose on unprofitable businesses.Related: With Whole Foods Purchase, Amazon Just Bought a Playground for Big DataGrocery stores that shut down will dry up foot traffic that helped nearby nail salons to coffee shops stay profitable, further adding to the real estate disruption. The good news is that as countless big box grocery stores close, we should see a rise in the prevalence of specialty stores such as Tony’s Meats & Market in Denver, Wegmans on the East Coast, and Trader Joe’s nationwide. Chains like these (and other newcomers) will expand and can help anchor and revive many developments.For real estate investors, this evolution will create lots of opportunity as developers and town planners rethink the best use for retail square footage. Investors that buy distressed assets will find plenty of properties coming on the market at 50 percent of their replacement value all the way down to pennies on the dollar.Investors in REITs, funds and other investment vehicles should take a close look at the underlying assets in those portfolios. Some may be overexposed to big box grocery stores and those that have not insulated against this coming risk should be re-evaluated. Conversely, investment groups that have cash on hand and a strategy to take advantage of the coming wave of distressed assets may offer a better investment alternative. Register Now » Brian Watson Chairman and CEO at Northstar Commercial Partners 5 min read Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. Opinions expressed by Entrepreneur contributors are their own. June 27, 2017 Guest Writer Next Article Image credit: NoDerog | Getty Images Amazon’s Whole Foods Deal Will Remake Strip Mallslast_img read more

Amateur Investors are Bullish About Cannabis That Has the Pros a Little

first_img –shares Peter Page Investing Retail stock investors are bullish — perhaps to a fault — about the prospects of publicly traded cannabis companies, according to a recent survey of 250 people who currently own marijuana related stocks.The survey, conducted in March by KCSA Strategic Communications, found that 90 percent of the investors reported their portfolios had appreciated, which might explain why 50 percent said they had sold non-cannabis stocks to buy cannabis stocks. “This is a fundamental shift taking place in society, right before our eyes, it’s exciting, it’s once in a lifetime, it’s lucrative and they want in on it,” said Lewis Goldberg, managing partner at KCSA and host of The Green Rush podcast.Related: Pay Attention to These 6 Cannabis Industry TrendsThe enthusiasm for cannabis has investors wisely spreading their money around — 52 percent said they own six or more cannabis stocks while 40 percent own 10 or more — but is also leading them to perhaps concentrate excessively on the sector, if not just one company in the sector. “Retail cannabis investors are significantly overweighting cannabis, which comprises more than a quarter of their overall portfolio, according to 40 percent of respondents,” KCSA noted in a report of the survey findings.Eighty percent of the investors surveyed said they plan to hold onto their cannabis investments for between one and ten years. “They understand the real value will be unlocked in years, not days or weeks,” Goldberg said.Related: How Risk Management Can Make Marijuana Businesses Bulletproof (or at Least Bullet Resistant)The survey found that individual investors show no concern that cannabis remains illegal under federal law. They believe the end of prohibition is inevitable and don’t believe the federal government will switch policy to crash the state-legal cannabis industry, which employs hundreds of thousands of people and has already attracted many billions in investments.“I think most Americans believe full federal legalization is a question of when, not if,” Goldberg said. “People are consuming (cannabis) and investing in it because they believe in it.’’Professional investors specializing in cannabis are less than thrilled by the enthusiasm of amateurs rushing to get in on what they think is the ground floor of the cannabis boom.Related: How the Green Rush Is Accelerating the Revolution In Smart Farming Technologies“Our biggest fear is people get sucked into the mania, they lose money and then think the industry is a joke when we know it’s real,” said Morgan Paxhia, who co-founded Poseidon Asset Management with his sister Emily Paxhia. “The general trend is this (industry) is very fast growing and there are very few other industries on the planet that have this sort of growth potential but it’s not a straight road. There are events that are impactful and you can’t just assume they will always keep going up.”Paxhia noted there are more than 300 publicly traded companies that can be broadly lumped into “cannabis.” They vary so much by sector — ancillary businesses like payment processors, manufacturers of needed equipment like grow lights, growers, medical marijuana and adult use, multi-state operators that might be retail dispensaries or vertically integrated companies, CBD and hemp, etc — and by the capabilities of their management team that stock selection is probably trickier in cannabis than in more established industries.Sean Stiefel, founder and managing partner of Navy Capital, warned that knowing a company is a “cannabis company” is not much to go on. The variables to consider are many. Publicly traded Canadian companies are “crazy” expensive, he said, while publicly traded US companies are more reasonably priced at around 20X EBITDA (“earnings before interest, taxes, depreciation and amortization,” a standard metric for evaluating company performance), though even the US stocks are relatively expensive because there are limited choices on US exchanges.Stiefel doesn’t think much of buy-and-hold as an investment strategy simply because the investor is hopeful they have bought shares in the cannabis equivalent of Apple or Google at the dawn of the tech boom. “I think holding anything for 10 years blindly is silly,” he said. “Have you owned anything for 10 years other than your house?” 4 min read Add to Queue Senior Editor for Green Entrepreneur The cannabis industry is certain to grow. That company you own shares in is not. Entrepreneur Staffcenter_img Image credit: 400tmax | Getty Images Download Our Free Android App May 6, 2019 Amateur Investors are Bullish About Cannabis. That Has the Pros a Little Worried. Free Green Entrepreneur App Keep up with the latest trends and news in the cannabis industry with our free articles and videos, plus subscribe to the digital edition of Green Entrepreneur magazine. Next Article last_img read more

Universal meningitis vaccination for college students may be too costly study suggests

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Dec 19 2018A computer-generated model developed by Johns Hopkins Medicine researchers adds to evidence that providing universal vaccination against meningitis B infection to students entering college may be too costly to justify the absolute number of cases it would prevent. The study also suggests that if vaccine developers could significantly lower the price, universal vaccination might be worth requiring on college campuses.In a report on the cost/benefit estimate published in the Dec. 17 issue of the American Journal of Preventive Medicine, researchers determined the cost per quality-adjusted life year (QALY)–a standard measure of the public policy value of medical interventions–to be $13.9 million if every entering college student in the United States were vaccinated. Historic expenditures and previous research, the investigators say, assume that society is willing to pay $150,000 per QALY. Put another way, the new study suggests that universal vaccination of the college student population would be considered cost-effective only if a vaccine series cost less than $65; the average current price is $324, according to study authors.”Despite the poor prognosis of meningitis B infection and the fairly reasonable cost of meningitis B (MenB) vaccination, the extreme rarity of this infection even amongst its peak in college-age individuals makes universal vaccination cost-ineffective,” says lead study author Ira Leeds, M.D., M.B.A., a postdoctoral research fellow in the Department of Surgery at the Johns Hopkins University School of Medicine. “Vaccinating 100,000 college students, for example, would prevent less than five cases of MenB,” adds Leeds. “Health care systems and public health programs do not have unlimited funds and such a small benefit makes support of universal vaccination economically untenable, even when accounting for individual, payer and community outbreak costs and productivity lost by society.”Although Leeds and his colleagues say their results fail to support a formal universal vaccination program, they caution that their model assumed all college students to have a generally well state of health. They also emphasized that MenB vaccine is safe and effective, and should remain accessible and an individual option. In addition, they say, those at high risk because of compromised immune systems or other pre-existing medical conditions should consider vaccination.Meningitis B is the most common form of meningococcal infection in young adults in the United States, with about 600 to 1,000 cases reported each year. But it affects only 30 per 100,000 U.S. college students, according to 2017 data gathered by the U.S. Centers for Disease Control and Prevention. The infection, however, is serious, and may cause severe inflammation of the brain and spine, and death in a small number of people. Each year, about 10-15 percent of Americans who contract MenB die.”Vaccines have become widely available within the past few years,” Leeds says, “but there’s very little evidence to suggest that they’re going to do much good given their high cost in a generally healthy population.”The study set out to assess cost-effectiveness and determine potentially favorable conditions for support of universal vaccination relative to the current standard of care, in which vaccination is an individual patient or parental decision. The investigators say their model considered the issue of universal vaccination from both a health sector perspective that incorporated individual and payer costs, and a societal perspective that further accounted for lifetime productivity losses among students experiencing MenB infection.Related StoriesScripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approachBordeaux University Hospital uses 3D printing to improve kidney tumor removal surgeryNew shingles vaccine reduces outbreaks of painful rash among stem cell transplant patientsTo come up with their results, the investigators developed a computerized “decision tree” algorithm to trace and track the incremental cost-effectiveness and cost per case averted by universal vaccination of incoming students at a midsize U.S. four-year college. They compared those costs against an informal, “random” vaccination program designed to mimic what this population might do if left to decide on its own whether to vaccinate. Each “student” in the model was assumed to be at equal risk for MenB infection and to be entering college at age 18 in generally good health.If universal vaccination was not offered initially, it was assumed that a suspected single case would lead to a belated universal vaccination campaign of all students, and faculty and staff members.The health sector perspective included direct medical costs borne by individual- and third-party payers over a four-year period. The societal perspective included additional costs of lost productivity from premature death, and long-term disability from MenB complications over the expected 80-year lifetime of a freshman college student. Estimates of infection rates and prevalence were obtained from government data, and universal vaccination was estimated to provide a 50 percent reduction in the probability of acquiring MenB infection, which is spread mainly by close contact with an infected person’s saliva–or spit.Researchers considered four clinically significant MenB complications for their assessment: death, chronic hearing loss, chronic neurologic disorder including epilepsy and intellectual disability, and limb amputation. The probabilities of these complications and outcomes of infection were taken from historical data reports, and for purposes of the computer model, deaths from meningitis were assumed to occur at the midpoint of college enrollment (two years).Vaccine prices were estimated from publicly reported vaccine price lists; vaccine administration costs were estimated to be 10 percent. The cost of an outbreak included vaccinations and staff to inoculate all students and faculty and staff members, plus antibiotic administration to 20 close contacts of an affected person. All cases of MenB infection were assumed to be treated with an inpatient hospital admission. All costs were adjusted to 2015 U.S. dollars based on the most common dates of existing data in the medical literature; investigators applied a 3 percent per year discounting for future costs/QALYs.Overall, the computer model predicted that a nonformal vaccination program was more cost-effective than universal vaccination from both the health sector and societal perspectives. Vaccinating each entering class of college students would cost an estimated $323,810 per campus per year. By contrast, an outbreak for a campus that would universally vaccinate after a case of infection was identified would cost $2.59 million per campus. Given the low incidence of MenB infections, a universal vaccination program would reduce the number of cases in four years from an estimated 9.2 cases per 1,000 campuses to 4.6 per 1,000 campuses.Therefore, Leeds and his team calculated, the incremental cost per QALY gained with universal vaccination was $13.9 million under the health sector perspective and $13.8 million under the societal perspective, compared to an assumed social willingness to pay $150,000 per QALY.Source: https://www.hopkinsmedicine.org/news/newsroom/news-releases/study-suggests-universal-meningitis-vaccination-is-not-cost-effective-for-college-studentslast_img read more

New microchip antibiotic testing platform determines right medication in just 67 hours

first_imgReviewed by James Ives, M.Psych. (Editor)Feb 6 2019We rely on antibiotics to treat bacterial infections, but the rise of antibiotic-resistant bacteria forces doctors and patients to contend with shifting treatment plans. Furthermore, current laboratory tests to determine what bacteria is causing a particular infection takes days to complete and, in cases of serious infection, the results are often too late for the patient.Mechanical engineers from the Korea Advanced Institute of Science and Technology recently developed a microchip antibiotic testing platform that takes only six to seven hours to determine the appropriate medication.”Trying to figure what drug to use at what dosage, in the fastest time possible, is key in successfully treating bacterial infections,” said Jessie Jeon, an author on the paper.Related StoriesStudy: Surveillance for antibiotic-resistant bacteria continues to be core focus for healthcare facilitiesStructure of bacteria responsible for traveler’s diarrhea decipheredNew methods to recognize antimicrobial resistant bacteria and how they workClinicians often treat life-threatening infections with a cocktail of antibiotics, hoping that one of the antibiotics will stop the bacterial infection. However, blanket-prescribing antibiotics contributes to the rise in bacterial resistance.”Figuring out the effect of different combinations of drugs in a simple manner is likely to have a big impact on health,” said Jeon. She explained that her team’s speedy microfluidic system was the first for which combinatorial treatments had been tested.The speed and success of the Korean team’s new antibiotic susceptibility testing system is due to two key innovative design features.The first feature was developing an antibiotic dosage range, crucial for calculating the minimum inhibitory dosage that prevents bacterial growth. By continually pumping antibiotics through the half-millimeter-wide channels in the microchip, the team establishes a dosage range through microchip within 30 minutes. A critical time saver, the dosage range enabled the team to determine the minimum inhibitory dosage within a single test.The second feature was using a convenient method to quantify bacterial growth within the microchip. Images were taken of the agar-encased bacteria and the difference in color between areas of agar at a higher antibiotic concentration, where no bacteria grew (which were dark), and the more reflective white regions, where bacterial colonies grew more easily, was quantified on a position-specific grayscale.Alignment of the five antibiotics tested in this new system with the clinical gold standard measurements suggests that the microchip system is sensitive enough for clinical application, Jeon added.”We can see that our assembly works pretty robustly with a single drug, and have also shown it can work with two drugs; now we want to further optimize the application to combinatorial drugs,” said Jeon. Source:https://www.aip.org/last_img read more

UK MPs pressure Zuckerberg to testify on Facebook data breach

British MPs threatened Tuesday to issue a formal summons to Facebook chief Mark Zuckerberg for him to testify over a major privacy row, after he declined to appear. Facebook chief Mark Zuckerberg was grilled by the US Congress last month but sent one of his executives to answer questions posed by the House of Commons culture and media committee Zuckerberg was grilled by the US Congress last month but sent one of his executives to answer questions posed by the House of Commons culture and media committee.MPs are investigating the use of Facebook data by a British political consultancy, Cambridge Analytica, as well as the phenomenon of “fake news” and Russia’s involvement in spreading misinformation online.In a letter to Facebook, committee chairman Damian Collins cited unconfirmed reports that Zuckerberg would testify to the European Parliament in May and asked him to come to London during the same trip.”We would like the session here to take place by 24 May,” he wrote.”It is worth noting that, while Mr Zuckerberg does not normally come under the jurisdiction of the UK parliament, he will do so the next time he enters the country.”We hope that he will respond positively to our request, but if not the committee will resolve to issue a formal summons for him to appear when he is next in the UK.”Ignoring a formal summons could invite action by the House of Commons, although in the past, the threat has usually been enough to make a witness appear.Facebook has admitted that up to 87 million users may have had their data hijacked by Cambridge Analytica, which worked for US President Donald Trump during his 2016 campaign.Collins noted that there are more than 40 million Facebook users in Britain “and they deserve to hear accurate answers” from Zuckerberg.A spokesman for the European Parliament said last week that an invitation had been sent to Zuckerberg to appear before MEPs “but we still wait for an answer… nothing has been decided yet”. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. UK MPs ask Facebook’s Zuckerberg to testify on data row Citation: UK MPs pressure Zuckerberg to testify on Facebook data breach (2018, May 1) retrieved 18 July 2019 from https://phys.org/news/2018-05-uk-mps-pressure-zuckerberg-testify.html Explore further © 2018 AFP read more

With an eye on past problems Facebook expands local feature

first_imgFacebook is cautiously expanding a feature that shows people local news and information, including missing-person alerts, road closures, crime reports and school announcements. A look at Facebook’s changes over the years in what you see Called “Today In,” the service shows people information from their towns and cities from such sources as news outlets, government entities and community groups. Facebook launched the service in January with six cities and expanded that to 25, then more. On Wednesday, “Today In” is expanding to 400 cities in the U.S.—and a few others in Australia.The move comes as Facebook tries to shake off its reputation as a hotbed for misinformation and elections-meddling and rather a place for communities and people to come together and stay informed.Here are some things to know about this effort, and why it matters:THE BIG PICTUREIt’s something users have asked for, the company says. Think of it as an evolution of a “trending” feature the company dropped earlier this year . That feature, which showed news articles that were popular among users, was rife with such problems as fake news and accusations of bias.Anthea Watson Strong, product manager for local news and community information, said her team learned from the problems with that feature.”We feel deeply the mistakes of our foremothers and forefathers,” she said.This time around, Facebook employees went to some of the cities they were launching in and met with users. They tried to predict problems by doing “pre-mortem” assessments, she said. That is, instead of a “post-mortem” where engineers dissect what went wrong after the fact, they tried to anticipate how people might misuse a feature—for financial gain, for example.Facebook isn’t saying how long it has been taking this “pre-mortem” approach, though the practice isn’t unique to the company. Nonetheless, it’s a significant step given that many of Facebook’s current problems stem from its failure to foresee how bad actors might co-opt the service.Facebook also hopes the feature’s slow rollout will prevent problems.HOW IT WORKSTo find out if “Today In” is available in your city or town, tap the “menu” icon with the three horizontal lines. Then scroll down until you see it. If you want, you can choose to see the local updates directly in your news feed.For now, the company is offering this only in small and mid-sized cities such as Conroe, Texas, Morgantown, West Virginia, and Santa Fe, New Mexico. Large cities such as New York or Los Angeles have added challenges, such as an abundance of news and information, and may need to be broken up into smaller neighborhoods.The posts in “Today In” are curated by artificial intelligence; there is no human involvement. The service aggregates posts from the Facebook pages for news organizations, government agencies and community groups like dog shelters. For this reason, a kid couldn’t declare a snow day, because “Today In” relies on the school’s official page. Discussion posts from local Facebook groups may also be included.For now, the information is tailored only by geography, but this might change. A person with no kids, for example, might not want to see updates from schools.SAFEGUARDS?Facebook uses software filters to weed out objectionable content, just as it does on people’s regular news feed. But the filters are turned up for “Today In.” If a good friend posts something a bit objectionable, you are still likely to see it because Facebook takes your friendship into account. But “Today In” posts aren’t coming from your friends, so Facebook is more likely to keep it out. Explore further © 2018 The Associated Press. All rights reserved. Citation: With an eye on past problems, Facebook expands local feature (2018, November 28) retrieved 17 July 2019 from https://phys.org/news/2018-11-eye-problems-facebook-local-feature.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

People Are Overdosing on Wasp Spray in West Virginia

first_img 5 Lethal Chemical Warfare Agents 9 Weird Ways You Can Test Positive for Drugs 5 Weird Effects of Bug Bites Several people in a county in West Virginia recently overdosed from wasp spray, which they used as an alternative to methamphetamine, according to news reports. Police in Boone County say they’ve seen a rise in residents abusing wasp spray to achieve a meth-like high, according to local news outlet WCHS. The practice is believed to have played a role in three overdoses in the county last week, WCHS reported. “People are making a synthetic type [of] methamphetamine out of wasp spray,” Sgt. Charles Sutphin, of the West Virginia State Police, told WCHS. [‘Breaking Bad’: 6 Strange Meth Facts]Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65954-wasp-spray-overdose-meth.html?jwsource=cl已复制直播00:0000:3500:35 The practice is known as “wasping,” and it has emerged as a concerning drug trend in recent years, according to a 2018 report from ABC News. Users either combine the wasp spray with meth, or use the spray by itself as a meth substitute. People can crystallize the spray liquid on hot metal sheets, which allows the substance to be inhaled or injected, ABC News reported. Bug sprays contain active ingredients called pyrethroids, which stun and kill insects; but in humans, the chemicals can interfere with nerve signaling, which can lead to abnormal sensations, and in some cases, seizures or paralysis, ABC News reported. The chemicals can also lead to increased heart rate, difficulty breathing, headache, nausea, problems with coordination, and swelling and burning sensations. Police in Boone County are working with medical centers to determine the best treatment for those who abuse the spray, WCHS reported. Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoBeverly Hills MDPlastic Surgeon Shares: “You Can Fill In Wrinkles At Home” (Here’s How)Beverly Hills MDUndoSecurity SaversWindows Users Advised To Do This TodaySecurity SaversUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoairdogusa.comThe World’s Best Washable Air Purifierairdogusa.comUndolast_img read more